Krokodil (Desomorphine): Effects, Risks & Treatment (2023)

What is Krokodil (Desomorphine)?

Krokodil (desomorphine) is a semi-synthetic opioid drug derived from codeine.1

The drug was first used in Russia and Ukraine before spreading to other countries.

Other names for Krokodil include:

  • Russian magic
  • Krocodil
  • Krok
  • Alligator drug

Russia and Ukraine are the most affected by Krokodil use because of the availability of codeine, a key ingredient for making this drug.

Research estimates that at least 100,000 people in Russia were confirmed to have injected Krokodil in 2011 alone.2

The name Krokodil comes from its toxic side effects. When injected, Krokodil results in a scaly black and green appearance at the injection site, resembling reptile or crocodile skin.

These toxic side effects are due to the harmful ingredients added to codeine when making Krokodil.

These additives include:

  • Hydrochloric acid (HCL)
  • Gasolene (Gasoline)
  • Lighter fluid
  • Red phosphorus
  • Paint thinner
  • Iodine

Like other opioids such as heroin, Krokodil is both a sedative (creates a feeling of calm) and an analgesic (pain reliever).

In many cases, Krokodil is used as a cheaper substitute for heroin.

Desomorphine (the active ingredient in Krokodil) is about ten times stronger than morphine, and its effects kick in much faster. However, unlike morphine, the euphoric effects of Krokodil last about two hours.

Krokodil was first used in 1935 to relieve pain and promote calmness before and after surgery.

However, Krokodil is no longer used and is classified as a Schedule I controlled drug in the United States due to its great potential for abuse and medical insignificance.3

(Video) Dangers Of Krokodil- Russia's Zombie Heroin (AKA Desomorphine)


Online Therapy Can Help

Over 3 million people use BetterHelp. Their services are:

  • Professional and effective
  • Affordable and convenient
  • Personalized and discreet
  • Easy to start

Find a Therapist

Answer a few questions to get started

Krokodil (Desomorphine): Effects, Risks & Treatment (1)

How to Take Krokodil Correctly

Most users take Krokodil via injection, although it may also be taken orally. Krokodil has a rapid onset of two to three minutes.

Since the effects last only two hours, most Krokodil users tend to inject the drug more frequently. This leads to quick physical addiction.

What are the Side Effects of Krokodil?

Short-term side effects include:

  • Slow or shallow breathing
  • Pain and swelling at the site of injection

Long-term side effects include:

  • Skin infections
  • Blood clots
  • Tissue infection
  • Inflamed veins (thrombophlebitis)4
  • Neurological impairment
  • Gangrene (death of body tissue due to interrupted blood flow)
  • Skin ulceration
  • Pneumonia
  • Meningitis
  • Liver and kidney damage
  • Blood poisoning (bacteremia)
  • Overdose
  • Respiratory issues (slowed or stopped breathing)
  • Death

Get Professional Help

BetterHelp can connect you to an addiction and mental health counselor.

Find a Therapist


Answer a few questions to get started

Krokodil (Desomorphine): Effects, Risks & Treatment (2)

What are the Risks of Krokodil?

When Krokodil is injected, it may cause vein damage and localized infections.

These infections have the potential to spread to other parts of the body and cause organ damage.5

If the limbs get infected, you may require an operation or amputation (removal of that part of the body).

Because Krokodil is a homemade opioid, the conditions under which it is prepared are a health risk to users.

Those preparing the drug are more likely to share preparation equipment, increasing the potential of contamination with other harmful substances.

In addition, users are likely to share needles, exposing themselves to the risk of infections such as HIV/AIDS and Hepatitis C.

The frequent use of Krokodil throughout the day may also contribute to non-sterile needle use and the potential for infections.

Even short-term Krokodil usage may result in serious health problems and death. Research estimates that most Krokodil users die within two years of addiction.6 The first use of Krokodil can lead to death in some cases.

Is Krokodil Addictive? What are the Symptoms?

Krokodil is very addictive. This, along with the side effects, makes it a hazardous drug.

Krokodil is about ten times more powerful than morphine and three times more potent than heroin. It is also very cheap.

According to the DEA, repeated administration of desomorphine at short intervals in cancer patients demonstrated that the drug is potentially addictive.7

The urge to continue using krokodil to prevent withdrawal symptoms may keep users from seeking addiction treatment, leading to chronic drug abuse.

Suddenly stopping Krokodil use will lead to withdrawal symptoms. They include:

  • Anxiety
  • Vomiting
  • Insomnia
  • Dilated pupils
  • Excessive sweating
  • Runny nose
  • Muscle aches
  • Irritability
  • Excessive tearing
  • Diarrhea

Although these withdrawal symptoms are very unpleasant, they are not life-threatening. However, the distress may be enough to keep someone stuck in an addictive lifestyle to avoid them.

Symptoms of Krokodil Addiction

  • Experiencing withdrawal symptoms
  • Inability to stop using
  • Continued use of Krokodil despite the adverse effects on your health
  • Isolating oneself from others to use the drug
  • Depression and lack of motivation
  • Neglecting personal responsibilities such as work or school

Phone, Video, or Live-Chat Support

BetterHelp provides therapy in a way that works for YOU. Fill out the questionnaire, get matched, begin therapy.

Get Started

Answer a few questions to get started

Krokodil (Desomorphine): Effects, Risks & Treatment (3)

(Video) Krokodil: Russia's Deadliest Drug (NSFW)

Can You Overdose on Krokodil?

Yes. You can overdose on Krokodil.

The symptoms of Krokodil overdose are similar to those of other opioids. They include:

  • Extreme drowsiness
  • Reduced or stopped breathing
  • Pinpoint pupils
  • Spasms or seizures
  • Extreme nausea and vomiting
  • Coma/unresponsiveness
  • Poor muscle coordination

In most instances, if these symptoms are not treated properly, death will occur.

Anyone experiencing these symptoms while using desomorphine or other opioids should seek emergency medical treatment.

4 Treatment Options for Krokodil Misuse & Addiction

Substance use treatment includes both psychological (mental) and physical healthcare.

Because of the significant physical harm caused by desomorphine addiction, most users should be treated in a supervised setting.

There are various treatment options for Krokodil addiction:

1. Medical Detox

If you're experiencing Krokodil withdrawal symptoms due to your addiction, a medically assisted detox program may help you overcome your physical dependency.

A Krokodil detox program offers treatment for Krokodil withdrawal symptoms, allowing you to feel secure, comfortable, and cared for.

It also helps in the prevention of relapse by giving professional support in a therapeutic setting.

2. Rehabilitation

People who have a history of krokodil addiction may find it highly beneficial to enroll in a drug treatment program after Krokodil detox.

Long-term addiction therapy may assist people in addressing the underlying causes of their addictive behaviors.

Addiction therapy will also help establish a solid foundation in recovery and develop essential life skills that help addicts remain clean in the long run.

The National Institute on Drug Abuse (NIDA) affirms that long-term (at least 90 days) offers the best chance of long-term recovery and reduces the risk of relapse.

Depending on your financial ability and treatment needs, you may choose to enroll in either an inpatient recovery program or an outpatient recovery program.8

Inpatient programs require the patient to stay in the facility for the entire duration of their recovery. It's most beneficial for severe addiction.

On the other hand, outpatient recovery centers allow patients to attend treatment while living their everyday lives. It's most preferred in mild addiction cases.

(Video) Radical Solutions to Cure Russia's Drug Addicts (2000)

If you're thinking about Krokodil drug rehab, you should expect to work alongside addiction treatment experts and sober peers to accomplish the following goals:

  • Learn about Krokodil addiction and the recovery process
  • Learn how to cope with triggers and cravings
  • Learn how to use a recovery program such as the 12-Step Program
  • Attend group and individual counseling sessions to resolve underlying psychological issues

These addiction treatment goals are achieved through various evidence-based treatment approaches, including cognitive-behavioral therapy (CBT), lectures, family counseling, and peer support.

3. Sober Living Programs

It often takes time to adapt to a clean lifestyle after treatment.

Most people need all the assistance and support they can receive, even after they complete their treatment.

A sober living program serves as a link between Krokodil treatment programs and independent sober living.

Sober living homes provide a secure, supportive, and sober living environment that fosters long-term recovery.

4. Aftercare Programs

Aftercare treatment consists of a series of outpatient group therapy sessions where recovered people may gather and discuss problems connected to addiction recovery.

Aftercare groups are a great way to build healthy connections, improve communication skills, discuss personal struggles, and support others in their recovery journey.

What's Next?

  • What Is Rehab Like?
  • Why Call an Addiction Hotline?
  • How to Sober Up
  • Tapering off of alcohol
  • What is Considered an Alcoholic?


Get matched with an affordable mental health counselor

Find a Therapist

Answer a few questions to get started

Krokodil (Desomorphine): Effects, Risks & Treatment (4)

(Video) Krokodil crosses over to U.S. from Russia


What are the side effects of desomorphine krokodil? ›

People who inject krokodil present a great variety of serious signs and symptoms, including thrombophlebitis, ulcerations, gangrene, and necrosis, quickly evolving to limb amputation and death. These effects are thought to result from the toxic components produced as byproducts during the homemade drug synthesis.

Why does krokodil damage skin? ›

1, 3, 8 However, krokodil contains many ingredients that are known to be toxic to the skin. It has been suggested that the presence of gasoline and hydrochloric acid in the injected solution induces discolored scaling and ulceration, whereas iodine has been to cause severe damage to the muscles and endocrine system.

Where is krokodil mostly used? ›

Introduction The narcotic drug krokodil is a semi-synthetic drug used as a cheap alternative to heroin. With its active ingredient desomorphine it is a highly addictive and destructive drug mainly used in Russia and Eastern Europe.

What are the health effects of krokodil? ›

What are symptoms of krokodil use?
  • Gangrene - a discolored (green, black) scale-like skin that resembles a crocodile.
  • Severe infection leading to amputation and/or death.
  • Severe tissue damage.

Why does krokodil cause skin necrosis? ›

These necrotic lesions might be explained by the extreme acidic nature of krokodil, substitution of the germinative, and keratin layers for connective tissue, or as consequence of blood vessel obstruction that may compromise desomorphine administration.

What is the life expectancy of a krokodil user? ›

Wherever on the body a user injects the drug, blood vessels burst and surrounding tissue dies, sometimes falling off the bone in chunks. That side effect has earned krokodil its other nickname: the zombie drug. The typical life span of an addict is just two or three years.

What is a fun fact about krokodil? ›

Krokodil's scientific name is not really Krokodil, it's scientific name is Desomorphine. Krokodil is the primary slang name for this drug. It is also called the “Zombie Drug” due to the fact that it can rapidly eat away at human flesh.

What is the street name for desomorphine? ›

Introduction: Desomorphine (Dihydrodesoxymorphine or dihydrodesoxymorphine-D) is a synthetic opioid-like substance synthesized in the 1930s in the United States. Its street names are “Krokodil” and “Crocodil.” Desomorphine produces an opiate-like action with a fast onset and brief action.

What effect does krokodil have on the face? ›

Krokodil's Extreme Effects

Desomorphine got its street name, krokodil, specifically because of its effects on the skin, turning it green and scaly before it sloughs off.

What is the skin rotting drug in the US? ›

People who inject drug mixtures containing xylazine also can develop severe wounds, including necrosis—the rotting of human tissue—that may lead to amputation.

When did krokodil become popular? ›

Krokodil (from the Russian кpoкoдил, or “crocodile”), which became popular in Russia around 2003, is a homemade opioid injectable drug synthesized from codeine (which is available over the counter in Russia) and other easily obtained materials.

Where was krokodil first used? ›

Krokodil, a flesh-eating drug which first surfaced in Russia more than a decade ago, has reportedly been found in the United States.

What is the cause of drug abuse Wikipedia? ›

The exact cause of substance abuse is not clear, but there are two predominant theories: either a genetic predisposition or a habit learned from others, which, if addiction develops, manifests itself as a chronic debilitating disease.

What is the problem with krokodil? ›

Long-term users who inject these caustic agents into their veins can develop extreme skin ulcerations, infections, and gangrene -- a discolored (green, grey, black) scale-like skin that resembles a crocodile, hence the street name “krokodil" or "crocodil".


1. How Russia Created the World’s Worst Street Drug | The War on Drugs
2. New drug trend has gruesome consequences for users
(KSAT 12)
3. "Tranq" The Skin Rotting Zombie Drug that Can't Be Reversed with Narcan
(Florida Training Academy)
4. Krokodil - Russia's Deadly 'Flesh Eating' Drug
(VICE Asia)
5. World's Scariest Drug (Documentary Exclusive)
6. Krokodil: The Flesh-Eating Drug Destroying Lives
(Using: My Story)


Top Articles
Latest Posts
Article information

Author: Wyatt Volkman LLD

Last Updated: 07/07/2023

Views: 6517

Rating: 4.6 / 5 (46 voted)

Reviews: 85% of readers found this page helpful

Author information

Name: Wyatt Volkman LLD

Birthday: 1992-02-16

Address: Suite 851 78549 Lubowitz Well, Wardside, TX 98080-8615

Phone: +67618977178100

Job: Manufacturing Director

Hobby: Running, Mountaineering, Inline skating, Writing, Baton twirling, Computer programming, Stone skipping

Introduction: My name is Wyatt Volkman LLD, I am a handsome, rich, comfortable, lively, zealous, graceful, gifted person who loves writing and wants to share my knowledge and understanding with you.